Aflatoxins are produced by species of Aspergillus flavus and Aspergillus parasiticus in various commodities including maize, rice, barley, wheat, sorghum, peanuts and copra. Asper-gillus flavus produces only aflatoxins B1 and B2 whereas A. parasiticus produces aflatoxins Bi, B2, Gi and G2. The toxicological effects of aflatoxins are dose-dependent. At high doses they are lethal if consumed, causing liver, myocardial and kidney tissue damage. At sub-lethal doses aflatoxins cause chronic toxicity, e.g. liver cirrhosis, and at low-level exposure, they are potent human hepatocellular carcinogens (Wild and Turner, 2002). Aflatoxins also are mutagenic and teratogenic and can depress cell-mediated immunity (Williams et al., 2004). Recently these toxins have been implicated in the stunting of children in Benin and Togo, where growth was reduced in children eating foods highly contaminated with aflatoxins introduced at weaning (Gong et al., 2002). Aflatoxin B1 acts synergistically with hepatitis B virus infection to increase its carcinogenic potency thirty-fold in hepatitis B surface antigen positive populations. The International Agency for Research on Cancer (IARC) has evaluated aflatoxin B1 as a Group 1 carcinogen producing liver cancer in humans (IARC, 1993).

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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