Compartment Syndrome

Local reaction to rattlesnake envenomation on an extremity may mimic compartment syndrome, however, it is an unusual complication. Current evidence suggests surgery does not improve outcome and should be limited to refractory cases. If pressure exceeds 30 mm Hg, Gold recommends giving additional vials of antivenom and 20% mannitol as an osmotic diuretic. Antivenin administration is clearly effective in preventing death after envenomation, plays a significant role in preventing local muscle necrosis, and is not augmented by fasciotomy and debridement (78,79).

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