History

Hepatitis E, formerly known as enterically transmitted non-A, non-B hepatitis, is a viral infection with clinical and epidemiological features of acute hepatitis. It is a principal cause of acute hepatitis in many developing nations and has been increasingly seen in industrialized countries. It is endemic in third world countries that have poor sanitary practices. Most cases in developed countries have been traced to travel to endemic areas; however, sporadic cases do occur in patients with no history of travel, suggesting possible reservoirs in developed countries (3).

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