Potential Targets For Discovery Of Antifungal Leads

Unlike the arena of development of antibacterial agents, in relative terms, where bacterial specific targets are abundant, it seems difficult to develop antifungal agents with a specific mode of action. Since, fungi as eukaryotic organism, have metabolism similar to those of mammal and plant hosts, most of antifungal agents discovered to be potentially active against plant pathogenic fungi have failed to survive during the testing process for practical usage. The following discussions will be of potential antifungal leads directed to fungal specific targets, with the examples of antifungal agents recently developed for clinical and agricultural uses.

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