Concentration micrograms of pLRV Coat protein100 g Tuber

Variety of potato Netherlands united Kingdom Germany Italy

Accent 0.17

Denmark

Asparges

Folva

Sava

Nicola

Jersey Royal

Cilena

Maris Piper

Francine

Novella

3.36

a PLRV virion levels detected in potato varieties commonly sold in the European Union. A market basket survey79 was conducted by Noteborn in 1998 to document exposure to PLRV and the PLRVrep protein.

Although infection reduces the yield and quality of potatoes, humans and animals have safely consumed such potatoes for centuries. Given that the PLRVrep protein was not detected in NewLeaf® Plus potatoes using current detection techniques, no increased exposure to the protein was expected and, having established a history of safe use, no additional protein safety assessment studies were considered to be necessary.

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4. Food and Agricultural Organization of the United Nations/World Health Organization (FAO/WHO), Safety aspects of genetically modified foods of plant origin. Report of a joint FAO/WHO expert consultation on foods derived from biotechnology, Geneva, Switzerland, 29 May-2 June, 2000, http://www.who.int/foodsafety/biotech/consult/en/ index.html (accessed December 18, 2006).

5. Konig, A. et al., Assessment of the safety of foods derived from genetically modified (GM) crops, Food Chem. Toxicol., 42, 1047, 2004.

6. Brijs, K., Bleukx, W. and Delcour, J.A., Proteolytic activities in dormant rye (Secale cereale L.) grain, J. Agric. Food Chem, 47, 3572, 1999.

7. Muntz, K. et al., Stored proteinases and the initiation of storage protein mobilization in seeds during germination and seedling growth, J. Exp. Botany, 52, 1741, 2001.

8. Shewry, P.R. and Halford, N.G., Cereal seed storage proteins: Structures, properties and role in grain utilization, J. Exp. Botany, 53, 947, 2002.

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