A consolidated risk assessment strategy is proposed for the introduction of proteins of diverse structure and function into food and feed crops. The strategy is based on, and aligned with, international guidelines and recommendations and can be adapted to evaluate the safety of new and improved varieties of biotechnology-derived crops that are under development. Based on the overall weight of evidence from assessing the safety of proteins of diverse structure and function used in food production and processing, as well as those introduced into biotechnology-derived crops, it is clear that introduced proteins can be safely used in the production of food and feed. The safety assessment tools are in place to and will continue be used as needed to ensure that food and feed derived from new varieties of biotechnology-derived crops can be safety consumed.

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